Thesis PDF

About the Authors

Baizhumatova M.P. – Neurologist, Deputy Head of the Regional Children's Rehabilitation Center "Zhansaya" Department of Health of the Turkestan region, Kentau, Republic of Kazakhstan.

Relevance

Cerebral palsy (CP) is a group of permanent, but not progressive, developmental disorders of movement and posture that cause limited activity due to neonatal or antenatal damage to the developing brain[1]. The most common motor syndrome in CP is spasticity, characterized by increased muscle tone and impaired selective movement control [2]. Without correction, spasticity leads to contractures, muscle shortening, pain syndrome, decreased quality of life, makes it difficult to carry out physical therapy and orthotics, and aggravates the psycho-emotional state of the child and family. Comprehensive rehabilitation with the participation of a multidisciplinary team is the main approach to the treatment of such patients [3,4]. Within the framework of this model, the use of botulinum toxin type A (BTA) is becoming an increasingly popular method of temporary and controlled correction of focal spasticity.

References

1. The Definition and Classification of Cerebral Palsy. (2007). Developmental medicine and child neurology, 49(s109), 1–44. https://doi.org/10.1111/j.1469-8749.2007.00001.x 
2. Oskoui, M., Coutinho, F., Dykeman, J., Jetté, N., & Pringsheim, T. (2013). An update on the prevalence of cerebral palsy: a systematic review and meta-analysis. Developmental medicine and child neurology, 55(6), 509–519. https://doi.org/10.1111/dmcn.12080 
3. Баранов, А. А., Намазова-Баранова, Л. С., Куренков, А. Л., Клочкова, О. А., Каримова, Х. М., Мамедъяров, А. М., ... & Бурсагова, Б. И. (2014). Комплексная оценка двигательных функций у пациентов с детским церебральным параличом.
4. Graham, H. K., Rosenbaum, P., Paneth, N., Dan, B., Lin, J. P., Damiano, D. L., Becher, J. G., Gaebler-Spira, D., Colver, A., Reddihough, D. S., Crompton, K. E., & Lieber, R. L. (2016). Cerebral palsy. Nature reviews. Disease primers, 2, 15082. https://doi.org/10.1038/nrdp.2015.82