JOURNAL

    Transcranial magnetic stimulation as a neuroplasticity modulator in the comprehensive rehabilitation of children with neuropsychiatric disorders

    Article PDF

    About the Authors

    Aizhan Turarbekova  - Physical Medicine and Rehabilitation Physician, NJSC "National Center for Children's Rehabilitation", Astana, Kazakhstan, This email address is being protected from spambots. You need JavaScript enabled to view it., https://orcid.org/0009-0008-4359-5506

    Marita Aitkulova - Physical Medicine and Rehabilitation Senior Physician, NJSC "National Center for Children's Rehabilitation", Astana, Kazakhstan, This email address is being protected from spambots. You need JavaScript enabled to view it., https://orcid.org/0009-0007-0516-9023

    Nazgul Dairova - Physical Medicine and Rehabilitation Physician, NJSC "National Center for Children's Rehabilitation", Astana, Kazakhstan, This email address is being protected from spambots. You need JavaScript enabled to view it., https://orcid.org/0009-0000-7819-3445 

    Abstract

    Neuropsychiatric disorders in children represent one of the leading problems in modern medicine, characterized by a steady increase in prevalence worldwide. Standard rehabilitation methods and pharmacotherapy often have limitations due to side effects and variability in treatment response. This article examines the effectiveness of a non-invasive neuromodulatory method – transcranial magnetic stimulation (TMS) – in medical practice. A review of international clinical data on the application of TMS in autism spectrum disorders (ASD), attention deficit hyperactivity disorder (ADHD), delayed psycho-speech development (DPSD), and cerebral palsy (CP) is presented. Furthermore, the results of our own retrospective study conducted at the National Center for Children's Rehabilitation (NCCR, Astana) are analyzed, showing a 27% increase in the effectiveness of standard rehabilitation when a TMS course is included. It is concluded that TMS is a safe and effective tool that creates favorable neurophysiological conditions for consolidating the rehabilitation effect.

    Keywords

    Transcranial magnetic stimulation, TMS, rehabilitation, neuroplasticity, autism spectrum disorders, ADHD, DPSD, cerebral palsy.

    References

    1. World Health Organization. Mental health of adolescents. Website. [Cited 19 May 2026]. Available from URL: https://www.who.int/news-room/fact-sheets/detail/adolescent-mental-health
    2. World Health Organization. Autism. Website. [Cited 19 May 2026]. Available from URL: https://www.who.int/news-room/fact-sheets/detail/autism-spectrum-disorders
    3. World Health Organization. Attention Deficit Hyperactivity Disorder (ADHD). (WHO-EM/MNH/214/E). Website. [Cited 19 May 2026]. Available from URL: https://iris.who.int/server/api/core/bitstreams/124a9607-3e2f-423c-aef0-2f79407971ad/content
    4. Khalil, M., Elweshahy, H., Abdelghani H., Omar T., Ahmed S. (2018). Quality of care provided to children with cerebral palsy, Alexandria, Egypt. Eastern Mediterranean Health Journal, 24(6), 522–531. https://doi.org/10.26719/2018.24.6.522
    5. World Health Organization. COVID-19 pandemic triggers 25% increase in prevalence of anxiety and depression worldwide. Website. [Cited 19 May 2026]. Available from URL: https://www.who.int/news/item/02-03-2022-covid-19-pandemic-triggers-25-increase-in-prevalence-of-anxiety-and-depression-worldwide
    6. Официальный интернет-ресурс Мажилиса Парламента РК. Ответ на депутатский запрос № ДЗ-105. Электронный документ. [Дата обращения 19 мая 2026]. Доступно по ссылке: https://mazhilis.parlam.kz/media/deputy_request_answer/documents/2026-04-30/%D0%9E%D1%82%D0%B2%D0%B5%D1%82_%D0%94%D0%97-105_8_4.pdf

    Ofitsial'nyy internet-resurs Mazhilisa Parlamenta Respubliki Kazakhstan. (2026). Otvet na deputatskiy zapros № DZ-105 ot 3 aprelya 2026 goda (Response to Deputy Inquiry No. DZ-105 dated April 3, 2026) [in Russian]. Elektronnyy dokument. [Data obrashcheniya: 19 maya 2026 g.]. Dostupno po ssylke: https://mazhilis.parlam.kz/media/deputy_request_answer/documents/2026-04-30/%D0%9E%D1%82%D0%B2%D0%B5%D1%82_%D0%94%D0%97-105_8_4.pdf

    1. Zheng, N., Zou, Z., Wang W., Dong F, He X., Ren J., Liu X., Zhang Y., Su Z. (2025). Efficacy of repetitive transcranial magnetic stimulation for consciousness recovery in children with disorders of consciousness following traumatic brain injury. Frontiers in Neurology, 16, 1678379. https://doi.org/10.3389/fneur.2025.1678379
    2. Li, F. Efficacy and Mechanism of rTMS in Children With ASD: an Open-label Clinical Trial (II). ClinicalTrials.gov Identifier: NCT05472870. Website. [Cited 19 May 2026]. Available from URL: https://clinicaltrials.gov/study/NCT05472870
    3. Weber, C. Transcranial Magnetic Stimulation (TMS) for Teens: A Breakthrough Treatment for Adolescent Depression. Behavioral Health News. Website. [Cited 19 May 2026]. Available from URL: https://behavioralhealthnews.org/transcranial-magnetic-stimulation-tms-for-teens-a-breakthrough-treatment-for-adolescent-depression/
    4. Cincinnati Children's. Neurology. Website. [Cited 19 May 2026]. Available from URL: https://www.cincinnatichildrens.org/service/n/neurology
    5. Arumí-Trujillo, C., Verdejo-Amengual F.J., Martínez-Navarro O., Vink J.J.T., Valenzuela-Pascual F. (2024). The effectiveness of non-invasive brain stimulation in enhanc-ing lower extremity function in children with spastic cerebral palsy: Protocol for a systematic review and meta-analysis. MethodsX, 14, 103141. https://doi.org/10.1016/j.mex.2024.103141
    6. The Deakin Lifespan Institute. Transcranial magnetic stimulation in autism. Website. [Cited 19 May 2026]. Available from URL: https://lifespan.deakin.edu.au/our-research/project/transcranial-magnetic-stimulation-in-autism/
    7. Yuan, L.-X., Wang, X.-K., Yang C., Zhang Q.-R., Ma S.-Z., Y.-F. Zang, Dong W.-Q. (2024). A systematic review of transcranial magnetic stimulation treatment for autism spectrum disorder. Heliyon, 10(11), e32251. https://doi.org/10.1016/j.heliyon.2024.e32251
    8. Minghui, Q., Wang, Y., Chen B., Sun S., Hu Q., Chen L., Xu S. (2025). The effects of rTMS and tDCS on repetitive/stereotypical behaviors, cognitive/executive functions in intellectually capable children and young adults with autism spectrum disorder: A systemat-ic review and meta-analysis of randomized controlled trials. Research in Developmental Disabilities, 164, 105076. https://doi.org/10.1016/j.ridd.2025.105076
    9. Fu, B., Zhou, X., Zhou X., Li X., Chen Z., Zhang Y., Du Q. (2024). Efficacy and Safety of TMS for Attention-Deficit Hyperactivity Disorder: A Systematic Review and Meta-Analysis. Brain and Behavior, 15, e70246. https://doi.org/10.1002/brb3.70246
    10. He, Y., Zhang, Q., Ma T.-T., Liang Y.-H., Guo R.-R., Li X.-S., Liu Q.-J., Feng T.-Y. (2024). Effect of repetitive transcranial magnetic stimulation-assisted training on lower limb motor function in children with hemiplegic cerebral palsy. BMC Pediatrics, 24, 136. https://doi.org/10.1186/s12887-024-04605-5
    11. Shen, X. Y., Zhao Z.-Z., Huang W. Y., Zhong J. G. (2025). Cognitive Im-provement in Children with Cerebral Palsy Following Combined Scalp Acupuncture and High-Frequency Repetitive Transcranial Magnetic Stimulation (rTMS): A Prospective Obser-vational Study. Cureus, 17(7), e87672. https://doi.org/10.7759/cureus.87672
    12. Wang, X., Zhang, Z., Li L., Gao Y., Cao Q. (2026). Efficacy and safety of transcranial magnetic stimulation in the treatment of children, adolescents and young adults with depression: A meta-analysis of randomized controlled trials. Journal of Affective Disorders, 392, 120132. https://doi.org/10.1016/j.jad.2025.120132
    13. Glatter, R., Muir, O. S. Transcranial magnetic stimulation for adolescent de-pression holds promise with limitations. Healio. Website. [Cited 19 May 2026]. Available from URL: https://www.healio.com/news/psychiatry/20260413/transcranial-magnetic-stimulation-for-adolescent-depression-holds-promise-with-limitations
    14. Zewdie, E., Ciechanski, P., Kuo H.C., Giuffre A., Kahl C., King R., Cole L., Godfrey H., Seeger T., Swansburg R., Damji O., Rajapakse T., Hodge J., Nelsone S., Selby B., Gan L., Jadavji Z., Larson J.R., MacMaster F., Yang J.F., Barlow K., Gorassini M., Brunton K., Kirton A. (2020). Safety and tolerability of transcranial magnetic and direct cur-rent stimulation in children: Prospective single center evidence from 3.5 million stimulations. Brain Stimulation, 13(3), 565–575. https://doi.org/10.1016/j.brs.2019.12.025

     

    200.png
    © 2026 All Rights Reserved.
    Whatsapp Instagram YouTube Запись на консультацию